Lifelines Biobank
Lifelines Cohort Study...
Description
Lifelines is a longitudinal multigenerational population cohort and biobank founded in 2006. Lifelines includes over 167,000 participants, covering 10% of the population in the three northern provinces of the Netherlands. We follow our participants...
General Design
- Type
- Biobank, Cohort study
- Cohort type
- Population cohort
- Data collection type
- Retrospective, Prospective
- Design
- Longitudinal
- Design description
- Lifelines participants undergo a physical examination and blood/urine collection once every 4-5 years, accompanied with extensive health- and lifestyle related questionnaires. In between assessments, follow-up questionnaires are sent out. Additional in-depth assessments on various topics are performed on request, often in subcohorts. See for more detail: http://wiki-lifelines.web.rug.nl/doku.php
- Design schematic
- Design schematic
- Start/End data collection
- 2006 (ongoing)
- Design papers
Population
- Countries
- Netherlands (the)
- Regions
- Drenthe, Friesland, Groningen
- Number of participants
- 167000
- Number of participants with samples
- 167000
- Population age groups
- Prenatal, All ages
Organisations
Additional organisations
- University Medical Centre Groningen (UMCG)Netherlands (the)https://www.umcg.nl/
- University of Groningen (RUG)Netherlands (the)https://www.rug.nl
Contributors
- dr. A. (Anouk) Marsman
- prof. dr. J.O. (Jochen) Mierau
Available Data & Samples
Data categories
- Biological samples
- Survey data
- Imaging data
- Physiological/Biochemical measurements
- Omics
- Genomics
- Transcriptomics
- Proteomics
- Metabolomics
Sample categories
- Blood
- Blood (whole)
- Blood Buffy Coat
- Fetal blood (Cord blood)
- Plasma
- Serum
- Fluids and Secretions
- Breath
- Feces
- Milk, Human
- Mouth swabs
- Nasal swabs
- Semen
- Urine
- 24h urine
- Urine, first morning
- Genetic material
- DNA
Areas of information
- Socio-demographic and economic characteristics
- Age/birthdate
- Sex/gender
- Twin
- Marital/partner status
- Family and household structure
- Education
- Residence
- Birthplace
- Citizenship and immigrant status
- Ethnicity, race and religion
- Language
- Labour force and retirement
- Income, possessions, and benefits
- Other socio-demographic and economic characteristics
- Lifestyle and behaviours
- Tobacco
- Alcohol
- Drugs
- Nutrition
- Breastfeeding
- Physical activity
- Transportation
- Sleep
- Sexual behaviours and orientation
- Leisure activities
- Technological devices
- Other and unspecified lifestyle information
- Birth, pregnancy and reproductive health history
- Puberty, menstruation, menopause and andropause
- Contraception
- Pregnancy, delivery and birth
- Fertility and sexual health
- Other reproductive health-related information
- Perception of health, quality of life, development and functional limitations
- Perception of health
- Quality of life
- Life course development
- Functional limitations
- Use of assistive devices
- Other perception of health, quality of life and functional limitation-related information
- Medication and supplements
- Medication and supplement intake
- Other and unspecified pharmacological interventions
- Non-pharmacological interventions
- Surgical interventions
- Physical therapy interventions
- Educational and health promotion interventions
- Health and community care services utilization
- Visits to health professionals
- Hospitalizations
- Community and social care
- Other health and community care
- Death
- Vital status
- Physical measures and assessments
- Physical characteristics
- Anthropometry
- Circulation and respiration
- Muscles, skeleton and mobility
- Skin and subcutaneous tissue
- Speech and voice
- Digestion
- Reproduction
- Other physical measures and assessments
- Laboratory measures
- Hematology
- Biochemistry
- Microbiology
- Virology
- Immunology
- Histology
- Genomics
- Other laboratory measures
- Cognition, personality and psychological measures and assessments
- Cognitive functioning
- Personality
- Psychological distress and emotions
- Other psychological measures and assessments
- Life events, life plans, beliefs and values
- Life events
- Beliefs and values
- Other life events, plans and beliefs
- Preschool, school and work life
- Preschool life
- School life
- Work life
- Other preschool, school or work life-related information
- Social environment and relationships
- Social network
- Social participation
- Social support
- Parenting and familial environment
- Other social environment characteristics
- Physical environment
- Housing characteristics
- Built environment/neighbourhood characteristics
- Chemical exposure
- Biological exposure
- Administrative information
- Identifiers
- Date and time-related information
- Questionnaire and interview-related information
- Physical and cognitive measure and biosample-related information
- Data and sample collection center-related information
- Other administrative information
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants |
|---|
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year |
|---|
Networks
Part of networks...
Publications
Access conditions
- Data access conditions
- no restriction
- general research use
- health or medical or biomedical research
- disease specific research
- Data use conditions
- publication required
- project specific restriction
- return to database or resource
- Data access fee
- true
- Release type
- Continuous
- Release description
- https://www.lifelines-biobank.com/researchers/working-with-us
- Linkage options
- https://www.lifelines-biobank.com/researchers/what-we-offer/linkage-with-external-sources
Funding & Acknowledgements
- Acknowledgements
- Acknowledgement of Lifelines in the title or abstract of all publications using Lifelines data, by using the phrases "Lifelines Cohort Study" or "Lifelines". Inclusion of the following sentences: "Lifelines is a multi-disciplinary prospective population-based cohort study examining in a unique three-generation design the health and health-related behaviours of 167,729 persons living in the North of the Netherlands. It employs a broad range of investigative procedures in assessing the biomedical, socio-demographic, behavioural, physical and psychological factors which contribute to the health and disease of the general population, with a special focus on multi-morbidity and complex genetics." https://www.lifelines-biobank.com/researchers/working-with-us/step-4-working-on-your-project/results/manuscript